USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: CLIC1_HUMAN USC-OGP 2-DE database:  CLIC1_HUMAN CLIC1_HUMAN General information about the entry View entry in simple text format Entry name CLIC1_HUMAN Primary accession number O00299 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Chloride intracellular channel protein 1; AltName: Full=Chloride channel ABP; AltName: Full=Nuclear chloride ion channel 27; Short=NCC27; AltName: Full=Regulatory nuclear chloride ion channel protein; Short=hRNCC;. Gene name Name=CLIC1 Synonyms=G6, NCC27 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0480: pI=5.05; Mw=30592 SPOT OGP-0483: pI=5.09; Mw=30517 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0766: pI=5.07; Mw=31444 SPOT OGP-0771: pI=5.10; Mw=30293 Cross-references UniProtKB/Swiss-Prot O00299; CLIC1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name CLIC1_HUMAN Primary accession number O00299 Secondary accession number(s) Q15089 Q502X1 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  March 15, 2017 (version 184) Name and origin of the protein Description RecName: Full=Chloride intracellular channel protein 1; AltName: Full=Chloride channel ABP; AltName: Full=Nuclear chloride ion channel 27; Short=NCC27; AltName: Full=Regulatory nuclear chloride ion channel protein; Short=hRNCC; Gene name Name=CLIC1 Synonyms=G6, NCC27 Encoded on Name=CLIC1; Synonyms=G6, NCC27 Keywords 3D-structure; Acetylation; Cell membrane; Chloride; Chloride channel; Complete proteome; Cytoplasm; Direct protein sequencing; Disulfide bond; Glutathionylation; Ion channel; Ion transport; Membrane; Nucleus; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport; Voltage-gated channel. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U93205; AAC25675.1; -; mRNA EMBL AF034607; AAD20437.1; -; mRNA EMBL AF109197; AAD26137.1; -; mRNA EMBL AJ012008; CAB46078.1; -; Genomic_DNA EMBL CR542071; CAG46868.1; -; mRNA EMBL AF129756; AAD18073.1; -; Genomic_DNA EMBL BA000025; BAB63376.1; -; Genomic_DNA EMBL AL662899; CAI18417.1; -; Genomic_DNA EMBL BC064527; AAH64527.1; -; mRNA EMBL BC095469; AAH95469.1; -; mRNA EMBL X87689; CAA61020.1; -; mRNA CCDS CCDS4719.1; -; . RefSeq NP_001274522.1; NM_001287593.1; . RefSeq NP_001274523.1; NM_001287594.1; . RefSeq NP_001279.2; NM_001288.4; . UniGene Hs.414565; -; . PDB 1K0M; X-ray; 1.40 A; A/B=1-241 PDB 1K0N; X-ray; 1.80 A; A/B=1-241 PDB 1K0O; X-ray; 1.75 A; A/B=1-241 PDB 1RK4; X-ray; 1.79 A; A/B=1-241 PDB 3O3T; X-ray; 1.70 A; A=1-241 PDB 3P8W; X-ray; 2.00 A; A=1-241 PDB 3P90; X-ray; 2.30 A; A=1-241 PDB 3QR6; X-ray; 1.78 A; A=1-241 PDB 3SWL; X-ray; 2.35 A; A=6-241 PDB 3TGZ; X-ray; 2.30 A; A/B=1-241 PDB 3UVH; X-ray; 1.84 A; A/B=1-241 PDB 4IQA; X-ray; 2.49 A; A/B=6-241 PDB 4JZQ; X-ray; 1.35 A; A/B=1-241 PDB 4K0G; X-ray; 1.40 A; A=2-241 PDB 4K0N; X-ray; 1.25 A; A=1-241 PDBsum 1K0M; -; . PDBsum 1K0N; -; . PDBsum 1K0O; -; . PDBsum 1RK4; -; . PDBsum 3O3T; -; . PDBsum 3P8W; -; . PDBsum 3P90; -; . PDBsum 3QR6; -; . PDBsum 3SWL; -; . PDBsum 3TGZ; -; . PDBsum 3UVH; -; . PDBsum 4IQA; -; . PDBsum 4JZQ; -; . PDBsum 4K0G; -; . PDBsum 4K0N; -; . ProteinModelPortal O00299; -; . SMR O00299; -; . BioGrid 107604; 57; . IntAct O00299; 42; . MINT MINT-1033423; -; . STRING 9606.ENSP00000364934; -; . TCDB 1.A.12.1.2; the intracellular chloride channel (clic) family; . iPTMnet O00299; -; . PhosphoSitePlus O00299; -; . SwissPalm O00299; -; . BioMuta CLIC1; -; . OGP O00299; -; . SWISS-2DPAGE O00299; -; . EPD O00299; -; . PaxDb O00299; -; . PeptideAtlas O00299; -; . PRIDE O00299; -; . TopDownProteomics O00299; -; . DNASU 1192; -; . Ensembl ENST00000375779; ENSP00000364934; ENSG00000213719; . Ensembl ENST00000375780; ENSP00000364935; ENSG00000213719; . Ensembl ENST00000375784; ENSP00000364940; ENSG00000213719; . Ensembl ENST00000383404; ENSP00000372896; ENSG00000206394; . Ensembl ENST00000383405; ENSP00000372897; ENSG00000206394; . Ensembl ENST00000395892; ENSP00000379229; ENSG00000213719; . Ensembl ENST00000400052; ENSP00000382926; ENSG00000206394; . Ensembl ENST00000400058; ENSP00000382931; ENSG00000206394; . Ensembl ENST00000415179; ENSP00000409247; ENSG00000226248; . Ensembl ENST00000418285; ENSP00000407791; ENSG00000226417; . Ensembl ENST00000420458; ENSP00000410965; ENSG00000226651; . Ensembl ENST00000422167; ENSP00000407429; ENSG00000226248; . Ensembl ENST00000423055; ENSP00000406968; ENSG00000226417; . Ensembl ENST00000423143; ENSP00000404589; ENSG00000223639; . Ensembl ENST00000423804; ENSP00000409979; ENSG00000230685; . Ensembl ENST00000425464; ENSP00000401292; ENSG00000223639; . Ensembl ENST00000431921; ENSP00000408357; ENSG00000226248; . Ensembl ENST00000433916; ENSP00000391395; ENSG00000226651; . Ensembl ENST00000434202; ENSP00000400532; ENSG00000226651; . Ensembl ENST00000435242; ENSP00000412217; ENSG00000226417; . Ensembl ENST00000438708; ENSP00000406088; ENSG00000226248; . Ensembl ENST00000438750; ENSP00000404037; ENSG00000223639; . Ensembl ENST00000442045; ENSP00000400280; ENSG00000226417; . Ensembl ENST00000447338; ENSP00000413330; ENSG00000230685; . Ensembl ENST00000447369; ENSP00000408094; ENSG00000230685; . Ensembl ENST00000451546; ENSP00000416211; ENSG00000223639; . Ensembl ENST00000456863; ENSP00000406335; ENSG00000226651; . Ensembl ENST00000457485; ENSP00000398056; ENSG00000230685; . Ensembl ENST00000614673; ENSP00000480256; ENSG00000230685; . Ensembl ENST00000614982; ENSP00000477623; ENSG00000206394; . Ensembl ENST00000616760; ENSP00000479808; ENSG00000213719; . Ensembl ENST00000618288; ENSP00000479501; ENSG00000226417; . Ensembl ENST00000619727; ENSP00000482255; ENSG00000226651; . Ensembl ENST00000621055; ENSP00000478930; ENSG00000226248; . Ensembl ENST00000622613; ENSP00000484581; ENSG00000223639; . GeneID 1192; -; . KEGG hsa:1192; -; . CTD 1192; -; . DisGeNET 1192; -; . GeneCards CLIC1; -; . HGNC HGNC:2062; CLIC1; . HPA CAB020825; -; . HPA CAB040557; -; . MIM 602872; gene; . neXtProt NX_O00299; -; . OpenTargets ENSG00000213719; -; . PharmGKB PA26588; -; . eggNOG ENOG410INGZ; Eukaryota; . eggNOG ENOG410ZZZX; LUCA; . GeneTree ENSGT00550000074477; -; . HOGENOM HOG000231548; -; . HOVERGEN HBG050994; -; . InParanoid O00299; -; . KO K05021; -; . OMA VCLKYRS; -; . OrthoDB EOG091G0IHT; -; . PhylomeDB O00299; -; . TreeFam TF315438; -; . SignaLink O00299; -; . ChiTaRS CLIC1; human; . EvolutionaryTrace O00299; -; . GeneWiki CLIC1; -; . GenomeRNAi 1192; -; . PRO PR:O00299; -; . Proteomes UP000005640; Chromosome 6; . Bgee ENSG00000206394; -; . CleanEx HS_CLIC1; -; . ExpressionAtlas O00299; baseline and differential; . Genevisible O00299; HS; . GO GO:0072562; C:blood microparticle; IDA:UniProtKB; . GO GO:0005903; C:brush border; TAS:UniProtKB; . GO GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005615; C:extracellular space; IDA:UniProtKB; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; IEA:Ensembl; . GO GO:0005635; C:nuclear envelope; IDA:MGI; . GO GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL; . GO GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; . GO GO:0031982; C:vesicle; IDA:UniProtKB; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0005254; F:chloride channel activity; IDA:MGI; . GO GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW; . GO GO:0006821; P:chloride transport; IDA:MGI; . GO GO:0070527; P:platelet aggregation; IMP:UniProtKB; . GO GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl; . GO GO:0051726; P:regulation of cell cycle; IEA:InterPro; . GO GO:0051881; P:regulation of mitochondrial membrane potential; IEA:Ensembl; . GO GO:0007165; P:signal transduction; TAS:UniProtKB; . Gene3D 1.20.1050.10; -; 1; . Gene3D 3.40.30.10; -; 1; . InterPro IPR002946; CLIC; . InterPro IPR030259; CLIC-1; . InterPro IPR010987; Glutathione-S-Trfase_C-like; . InterPro IPR004045; Glutathione_S-Trfase_N; . InterPro IPR012336; Thioredoxin-like_fold; . PANTHER PTHR11260:SF473; PTHR11260:SF473; 1; . Pfam PF13409; GST_N_2; 1; . PRINTS PR01263; INTCLCHANNEL; . SFLD SFLDG01175; Main.10_; 1; . SUPFAM SSF47616; SSF47616; 1; . SUPFAM SSF52833; SSF52833; 1; . TIGRFAMs TIGR00862; O-ClC; 1; . PROSITE PS50405; GST_CTER; 1; .

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